Item Type | Name |
Concept
|
Aconitate Hydratase
|
Concept
|
Age Factors
|
Concept
|
Administration, Inhalation
|
Concept
|
Aorta, Thoracic
|
Concept
|
Ankle
|
Concept
|
Acridines
|
Concept
|
Acetylcysteine
|
Concept
|
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
|
Concept
|
Algorithms
|
Concept
|
Aminorex
|
Concept
|
Blood Flow Velocity
|
Concept
|
Blood Pressure
|
Concept
|
Aging
|
Concept
|
Administration, Oral
|
Concept
|
Bundle-Branch Block
|
Concept
|
Energy Intake
|
Concept
|
Carbazoles
|
Concept
|
Cardiac Output
|
Concept
|
Angiography
|
Concept
|
Analysis of Variance
|
Concept
|
Cyclohexanols
|
Concept
|
Benzamides
|
Concept
|
Benzoates
|
Concept
|
Dithionitrobenzoic Acid
|
Concept
|
Biotin
|
Concept
|
Body Temperature
|
Concept
|
Biopsy, Needle
|
Concept
|
Body Weight
|
Concept
|
Bone Marrow
|
Concept
|
Electrons
|
Concept
|
Carbon Monoxide
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
Concept
|
Cattle
|
Concept
|
Cell Separation
|
Concept
|
Ischemic Attack, Transient
|
Concept
|
Breath Tests
|
Concept
|
Chromosomes, Human, Pair 1
|
Concept
|
Cholesterol, Dietary
|
Concept
|
Catalase
|
Concept
|
Free Radicals
|
Concept
|
Chicago
|
Concept
|
Blood Gas Analysis
|
Concept
|
Blood Pressure Determination
|
Concept
|
Bradykinin
|
Concept
|
Genetic Vectors
|
Concept
|
Connective Tissue Diseases
|
Concept
|
Creatinine
|
Concept
|
Coronary Artery Disease
|
Concept
|
Diabetes Mellitus, Type 2
|
Concept
|
Homozygote
|
Concept
|
Culture Media
|
Concept
|
Coronary Circulation
|
Concept
|
Immune System
|
Concept
|
Diet Surveys
|
Concept
|
Injections, Intramuscular
|
Concept
|
Endothelium, Vascular
|
Concept
|
Equipment Design
|
Concept
|
Disulfides
|
Concept
|
Dithiothreitol
|
Concept
|
Cause of Death
|
Concept
|
Dogs
|
Concept
|
Echocardiography
|
Concept
|
Deferoxamine
|
Concept
|
Ductus Arteriosus, Patent
|
Concept
|
Fluoresceins
|
Concept
|
Health Surveys
|
Concept
|
Electrophysiology
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Ethers, Cyclic
|
Concept
|
Delivery of Health Care
|
Concept
|
Clitoris
|
Concept
|
Factor VIII
|
Concept
|
Femoral Vein
|
Concept
|
Mass Screening
|
Concept
|
Depression
|
Concept
|
Diagnostic Imaging
|
Concept
|
Cross-Sectional Studies
|
Concept
|
Electron Transport Complex IV
|
Concept
|
Dobutamine
|
Concept
|
Double-Blind Method
|
Concept
|
Drug Evaluation, Preclinical
|
Concept
|
Drug Therapy, Combination
|
Concept
|
Fibrinogen
|
Concept
|
Fibroblasts
|
Concept
|
Electric Conductivity
|
Concept
|
Electrocardiography
|
Concept
|
Enzyme Activation
|
Concept
|
Gene Expression Regulation
|
Concept
|
Genes, Dominant
|
Concept
|
Fasting
|
Concept
|
Feasibility Studies
|
Concept
|
Fetal Heart
|
Concept
|
Nifedipine
|
Concept
|
Isoxazoles
|
Concept
|
Forced Expiratory Volume
|
Concept
|
Dietary Fats, Unsaturated
|
Concept
|
DNA (Cytosine-5-)-Methyltransferases
|
Concept
|
Cardiac Catheterization
|
Concept
|
Dopamine
|
Concept
|
Drug Combinations
|
Concept
|
Ductus Arteriosus
|
Concept
|
Dyspnea
|
Concept
|
Hydrogen Peroxide
|
Concept
|
Hyperlipoproteinemia Type II
|
Concept
|
Enzyme Induction
|
Concept
|
Herbicides
|
Concept
|
Hexokinase
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Infusions, Intravenous
|
Concept
|
Gene Amplification
|
Concept
|
Guanylate Cyclase
|
Concept
|
Health Services Accessibility
|
Concept
|
Luminol
|
Concept
|
Lung Diseases
|
Concept
|
Macrophages
|
Concept
|
Iron-Sulfur Proteins
|
Concept
|
Ketanserin
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Metformin
|
Concept
|
Labor, Obstetric
|
Concept
|
Hydrolysis
|
Concept
|
Phenylephrine
|
Concept
|
Phosphatidylcholines
|
Concept
|
Pilot Projects
|
Concept
|
Mice, Transgenic
|
Concept
|
Minnesota
|
Concept
|
Models, Cardiovascular
|
Concept
|
Nitrogen Oxides
|
Concept
|
Pneumonia, Viral
|
Concept
|
Meclofenamic Acid
|
Concept
|
Medical History Taking
|
Concept
|
Exercise Test
|
Concept
|
Extracellular Matrix
|
Concept
|
Immunohistochemistry
|
Concept
|
Organ Size
|
Concept
|
Glycogen
|
Concept
|
Granulomatous Disease, Chronic
|
Concept
|
Pancreatic Elastase
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mice, Nude
|
Concept
|
Random Allocation
|
Concept
|
Molecular Biology
|
Concept
|
Mutation
|
Concept
|
Myocardial Contraction
|
Concept
|
Cricetinae
|
Concept
|
Herpes Simplex
|
Concept
|
Pergolide
|
Concept
|
Neutrophils
|
Concept
|
Nitric Oxide
|
Concept
|
Laparoscopy
|
Concept
|
Phosphodiesterase Inhibitors
|
Concept
|
Lung Neoplasms
|
Concept
|
Rodentia
|
Concept
|
Partial Pressure
|
Concept
|
Peptides, Cyclic
|
Concept
|
Methylene Blue
|
Concept
|
Persistent Fetal Circulation Syndrome
|
Concept
|
Practice Patterns, Physicians'
|
Concept
|
Phenylurea Compounds
|
Concept
|
Phospholipases
|
Concept
|
Oxygen
|
Concept
|
Feeding Behavior
|
Concept
|
Fetus
|
Concept
|
Porphyrins
|
Concept
|
Drug Prescriptions
|
Concept
|
Epoprostenol
|
Concept
|
Thromboembolism
|
Concept
|
Piperazines
|
Concept
|
Pressure
|
Concept
|
Prostaglandins
|
Concept
|
Protein Processing, Post-Translational
|
Concept
|
Pulmonary Gas Exchange
|
Concept
|
Pulmonary Edema
|
Concept
|
Pulmonary Wedge Pressure
|
Concept
|
Pyridines
|
Concept
|
Forecasting
|
Concept
|
Glomerular Mesangium
|
Concept
|
Glutamine
|
Concept
|
Regression Analysis
|
Concept
|
Renal Circulation
|
Concept
|
Rabbits
|
Concept
|
Registries
|
Concept
|
Risk Factors
|
Concept
|
Pulmonary Circulation
|
Concept
|
Pyrrolidines
|
Concept
|
Somatostatin
|
Concept
|
Rotenone
|
Concept
|
Cohort Studies
|
Concept
|
Radionuclide Angiography
|
Concept
|
Rats, Nude
|
Concept
|
Scleroderma, Systemic
|
Concept
|
Respiratory Function Tests
|
Concept
|
Interleukin-6
|
Concept
|
Health Knowledge, Attitudes, Practice
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Swine
|
Concept
|
Thrombin
|
Concept
|
Hematologic Tests
|
Concept
|
Hemodynamics
|
Concept
|
Sheep
|
Concept
|
House Calls
|
Concept
|
Humans
|
Concept
|
Hypercholesterolemia
|
Concept
|
Hypertension, Pulmonary
|
Concept
|
Tomography, Emission-Computed, Single-Photon
|
Concept
|
Incidence
|
Concept
|
Linear Models
|
Concept
|
Single-Blind Method
|
Concept
|
Tomography, X-Ray Computed
|
Concept
|
Superoxides
|
Concept
|
Specific Pathogen-Free Organisms
|
Concept
|
Thrombin Time
|
Concept
|
Ultrasonography
|
Concept
|
Vasoconstriction
|
Concept
|
Stroke Volume
|
Concept
|
Hypertrophy, Right Ventricular
|
Concept
|
Practice Guidelines as Topic
|
Concept
|
Warfarin
|
Concept
|
Thiophenes
|
Concept
|
Genetic Variation
|
Concept
|
3',5'-Cyclic-GMP Phosphodiesterases
|
Concept
|
Echocardiography, Doppler
|
Concept
|
Transduction, Genetic
|
Concept
|
Herpesvirus 1, Human
|
Concept
|
Proportional Hazards Models
|
Concept
|
Randomized Controlled Trials as Topic
|
Concept
|
Risk Assessment
|
Concept
|
Cell Culture Techniques
|
Concept
|
Drug Resistance, Neoplasm
|
Concept
|
Oleic Acid
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
rho GTP-Binding Proteins
|
Concept
|
rhoB GTP-Binding Protein
|
Concept
|
Uncoupling Agents
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Guanosine 5'-O-(3-Thiotriphosphate)
|
Concept
|
Ventricular Function, Left
|
Concept
|
4-Aminopyridine
|
Concept
|
Cell Adhesion Molecules
|
Concept
|
Up-Regulation
|
Concept
|
5,8,11,14-Eicosatetraynoic Acid
|
Concept
|
Antigens, Differentiation, Myelomonocytic
|
Concept
|
Prevalence
|
Concept
|
G1 Phase
|
Concept
|
Cardiopulmonary Resuscitation
|
Concept
|
Exercise
|
Concept
|
Fatty Acids, Omega-3
|
Concept
|
Antigens, CD
|
Concept
|
Nisoldipine
|
Concept
|
Bepridil
|
Concept
|
Lupus Erythematosus, Systemic
|
Concept
|
Chi-Square Distribution
|
Concept
|
Comorbidity
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Rats, Wistar
|
Concept
|
Case-Control Studies
|
Concept
|
RNA Interference
|
Concept
|
Genes, Reporter
|
Concept
|
Treatment Outcome
|
Concept
|
NADH Dehydrogenase
|
Concept
|
National Institutes of Health (U.S.)
|
Concept
|
Guidelines as Topic
|
Concept
|
Arachidonic Acid
|
Concept
|
Cyclooxygenase Inhibitors
|
Concept
|
Gene Transfer Techniques
|
Concept
|
Mice, Knockout
|
Concept
|
Cell Proliferation
|
Concept
|
Telomerase
|
Concept
|
Cytochrome P-450 CYP2E1
|
Concept
|
Inhibitor of Apoptosis Proteins
|
Concept
|
Glucose Intolerance
|
Concept
|
Ventricular Remodeling
|
Concept
|
Dietary Sucrose
|
Concept
|
Mutation, Missense
|
Concept
|
Venous Thrombosis
|
Concept
|
Metabolic Syndrome
|
Concept
|
Cross-Over Studies
|
Concept
|
Ozone
|
Concept
|
Drug Dosage Calculations
|
Concept
|
GTP Phosphohydrolases
|
Concept
|
Reactive Oxygen Species
|
Concept
|
Receptors, Dopamine D1
|
Concept
|
Fatal Outcome
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
Concept
|
Gold Colloid
|
Concept
|
Myofibroblasts
|
Concept
|
Phosphodiesterase 5 Inhibitors
|
Concept
|
Microdissection
|
Concept
|
MAP Kinase Kinase 4
|
Concept
|
Positron-Emission Tomography
|
Concept
|
Proteomics
|
Concept
|
COS Cells
|
Concept
|
Microscopy, Confocal
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p16
|
Concept
|
5' Untranslated Regions
|
Concept
|
Neovascularization, Physiologic
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
3' Untranslated Regions
|
Concept
|
Quality-Adjusted Life Years
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
Concept
|
rhoA GTP-Binding Protein
|
Concept
|
DNA, Intergenic
|
Concept
|
Tocopherols
|
Concept
|
Thrombospondins
|
Concept
|
Phenyl Ethers
|
Concept
|
Physical Examination
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Prostaglandins F
|
Concept
|
Mice
|
Concept
|
Prostaglandins, Synthetic
|
Concept
|
Pulmonary Diffusing Capacity
|
Concept
|
Pyrazoles
|
Concept
|
Pyrimidines
|
Concept
|
Pyrroles
|
Concept
|
Surveys and Questionnaires
|
Concept
|
Radionuclide Imaging
|
Concept
|
Rats, Inbred Strains
|
Concept
|
Serum Albumin
|
Concept
|
Severity of Illness Index
|
Concept
|
Substance P
|
Concept
|
Electron Transport Complex I
|
Concept
|
Angiogenesis Inducing Agents
|
Concept
|
Metabolic Equivalent
|
Concept
|
Rats
|
Concept
|
High-Throughput Nucleotide Sequencing
|
Concept
|
Genotyping Techniques
|
Concept
|
Real-Time Polymerase Chain Reaction
|
Concept
|
Staphylococcus aureus
|
Concept
|
Vascular Resistance
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Western
|
Concept
|
Down-Regulation
|
Concept
|
STAT2 Transcription Factor
|
Concept
|
Multivariate Analysis
|
Concept
|
Logistic Models
|
Concept
|
Survival Analysis
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
Thyroid Neoplasms
|
Concept
|
Cyclosporine
|
Concept
|
Transfection
|
Concept
|
Trimetazidine
|
Concept
|
Ventilation-Perfusion Ratio
|
Concept
|
von Willebrand Diseases
|
Concept
|
Xanthenes
|
Concept
|
8,11,14-Eicosatrienoic Acid
|
Concept
|
Blotting, Northern
|
Concept
|
Reproducibility of Results
|
Concept
|
Patient Satisfaction
|
Concept
|
Genetic Therapy
|
Concept
|
HLA-DP alpha-Chains
|
Concept
|
Lung Diseases, Interstitial
|
Concept
|
Ion-Selective Electrodes
|
Concept
|
Genome, Human
|
Concept
|
Gene Expression Regulation, Enzymologic
|
Concept
|
Survival Rate
|
Concept
|
Odds Ratio
|
Concept
|
Ventricular Function, Right
|
Concept
|
Magnetic Resonance Imaging, Cine
|
Concept
|
Telemedicine
|
Concept
|
DNA Methylation
|
Concept
|
NADPH Oxidases
|
Concept
|
Echocardiography, Transesophageal
|
Concept
|
Dietary Supplements
|
Concept
|
Dexfenfluramine
|
Concept
|
Gene Silencing
|
Concept
|
Xenograft Model Antitumor Assays
|
Concept
|
Gene Targeting
|
Concept
|
Hepatopulmonary Syndrome
|
Concept
|
Placental Circulation
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
E2F1 Transcription Factor
|
Concept
|
Kv Channel-Interacting Proteins
|
Concept
|
Transcriptome
|
Concept
|
Pulmonary Disease, Chronic Obstructive
|
Concept
|
Genome-Wide Association Study
|
Concept
|
X-Ray Microtomography
|
Concept
|
AMP-Activated Protein Kinases
|
Concept
|
Ventilator-Induced Lung Injury
|
Concept
|
Dynamins
|
Concept
|
Tumor Microenvironment
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
Concept
|
Kaplan-Meier Estimate
|
Concept
|
Latent TGF-beta Binding Proteins
|
Concept
|
rho-Associated Kinases
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
Concept
|
Cyclic Nucleotide Phosphodiesterases, Type 5
|
Concept
|
Growth Differentiation Factor 2
|
Concept
|
Cyclin B1
|
Concept
|
Antibodies, Antinuclear
|
Concept
|
Coronary Artery Bypass
|
Concept
|
Autopsy
|
Concept
|
Benzenesulfonates
|
Concept
|
Bronchopulmonary Dysplasia
|
Concept
|
Chromosome Aberrations
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Cyanamide
|
Concept
|
Diabetes Mellitus
|
Concept
|
Diastole
|
Concept
|
Dietary Fats
|
Concept
|
Disease Models, Animal
|
Concept
|
Epinephrine
|
Concept
|
Factor VII
|
Concept
|
Fetal Hypoxia
|
Concept
|
Fibrinolytic Agents
|
Concept
|
Follow-Up Studies
|
Concept
|
Food Preferences
|
Concept
|
Food, Formulated
|
Concept
|
Genetic Counseling
|
Concept
|
Gestational Age
|
Concept
|
Glucose
|
Concept
|
Guanosine Diphosphate
|
Concept
|
Health Personnel
|
Concept
|
Heart Rate
|
Concept
|
Hernia, Diaphragmatic
|
Concept
|
Kinetics
|
Concept
|
Longitudinal Studies
|
Concept
|
Lung Diseases, Obstructive
|
Concept
|
Lymphocytes
|
Concept
|
Magnetic Resonance Imaging
|
Concept
|
Microelectrodes
|
Concept
|
Monitoring, Physiologic
|
Concept
|
Niacinamide
|
Concept
|
Norepinephrine
|
Concept
|
Panic
|
Concept
|
Phosphocreatine
|
Concept
|
Phosphoric Diester Hydrolases
|
Concept
|
Predictive Value of Tests
|
Concept
|
Prospective Studies
|
Concept
|
Pulmonary Embolism
|
Concept
|
Rats, Mutant Strains
|
Concept
|
Receptors, Adrenergic, beta
|
Concept
|
Recombinant Fusion Proteins
|
Concept
|
Respiration, Artificial
|
Concept
|
Retrospective Studies
|
Concept
|
Sincalide
|
Concept
|
Syncope
|
Concept
|
Systole
|
Concept
|
Vasodilation
|
Concept
|
Vitamin A
|
Concept
|
Wisconsin
|
Concept
|
Dinoprost
|
Concept
|
Thrombolytic Therapy
|
Concept
|
Gene Expression Regulation, Neoplastic
|
Concept
|
Cytokines
|
Concept
|
Databases, Factual
|
Concept
|
Iloprost
|
Concept
|
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
|
Concept
|
Okadaic Acid
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Polymorphism, Single Nucleotide
|
Concept
|
Optic Atrophy, Autosomal Dominant
|
Concept
|
MicroRNAs
|
Concept
|
Epigenesis, Genetic
|
Concept
|
Microscopy, Electron, Transmission
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
Concept
|
Kv1.5 Potassium Channel
|
Concept
|
Inhibitor of Differentiation Proteins
|
Concept
|
G-Protein-Coupled Receptor Kinase 2
|
Concept
|
Lung Injury
|
Concept
|
HLA-DP beta-Chains
|
Academic Article
|
Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue.
|
Academic Article
|
Measurement of nitric oxide in biological models.
|
Academic Article
|
Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.
|
Academic Article
|
Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels.
|
Academic Article
|
Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing.
|
Academic Article
|
Sildenafil: from the bench to the bedside.
|
Academic Article
|
Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
|
Academic Article
|
GTP (gammaS) and GDP (betaS) as electron donors: new wine in old bottles.
|
Academic Article
|
Coronary nitric oxide production in response to exercise and endothelium-dependent agonists.
|
Academic Article
|
Triple-bonded unsaturated fatty acids are redox active compounds.
|
Academic Article
|
Voltage-gated potassium channels in human ductus arteriosus.
|
Academic Article
|
Innovative strategic Canadian research training from TomorrOw's Research Cardiovascular Health Care Professionals (TORCH).
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Acute oxygen-sensing mechanisms.
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An evidence-based approach to the management of pulmonary arterial hypertension.
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Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension.
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The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
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Images in cardiovascular medicine. Untreated 37-year-old homozygous familial hypercholesterolemic smoker.
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The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
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Dilated cardiomyopathy and left bundle branch block associated with ingestion of colloidal gold and silver is reversed by British antiLewisite and vitamin E: the potential toxicity of metals used as health supplements.
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Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
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O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
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ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog.
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Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
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Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension.
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Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation.
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A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension.
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The role of redox changes in oxygen sensing.
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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
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Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
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Hydroxylamine is a vasorelaxant and a possible intermediate in the oxidative conversion of L-arginine to nitric oxide.
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Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.
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Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH.
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Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.
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Chronic primary and secondary thromboembolic pulmonary hypertension.
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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
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Exercise thallium testing in ventricular preexcitation.
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Redox status in the control of pulmonary vascular tone.
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Effects of dietary fish oil on lung phospholipid fatty acid composition and intrinsic pulmonary vascular reactivity.
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Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
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Identification of opioid receptors in the immune system using a novel combination of selective opioid ligands and indirect phycoerythrin immunofluorescence.
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Cellular and molecular basis of pulmonary arterial hypertension.
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NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
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Hypoxic pulmonary vasoconstriction.
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Epigenetic mechanisms of pulmonary hypertension.
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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
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The role of redox signaling in epigenetics and cardiovascular disease.
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GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.
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Differences in food habits and cardiovascular disease risk factors among Native Americans with and without diabetes: the Inter-Tribal Heart Project.
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Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission.
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SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
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Noninvasive cardiac output measurements in patients with pulmonary hypertension.
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Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
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Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.
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A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017.
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Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.
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Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.
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Pulmonary arterial hypertension: pathogenesis and clinical management.
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Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.
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Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.
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Riociguat for pulmonary hypertension--a glass half full.
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Mitochondrial dynamics--mitochondrial fission and fusion in human diseases.
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Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
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An official American Thoracic Society Statement: pulmonary hypertension phenotypes.
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The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure.
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Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.
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Mitochondrial fission and fusion in human diseases.
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Right ventricular adaptation and failure in pulmonary arterial hypertension.
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Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research.
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Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension.
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A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension.
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Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
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Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again.
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Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease.
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Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
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Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities.
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.
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Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
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Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction".
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Home Virtual Visits for Outpatient Follow-Up Stroke Care: Cross-Sectional Study.
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
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Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
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An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
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Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension.
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Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
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Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics.
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Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
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Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion.
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Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
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Providing care for the 99.9% during the COVID-19 pandemic: How ethics, equity, epidemiology, and cost per QALY inform healthcare policy.
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Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
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Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
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Evaluation of the Impact of an Echocardiographic Diagnosis of Pulmonary Hypertension on Patient Outcomes.
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Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
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Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice.
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Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer.
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Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension.
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Hemodynamic Characteristics and Outcomes of Pulmonary Hypertension in Patients Undergoing Tricuspid Valve Repair or Replacement.
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Left Main Coronary Artery Compression in Pulmonary Arterial Hypertension: Percutaneous Treatment to Improve Symptoms.
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Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension.
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The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
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Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
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PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
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Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop.
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Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.
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Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility.
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Mitochondria in human neutrophils mediate killing of Staphylococcus aureus.
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Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
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The comprehensive transcriptome of human ductus arteriosus smooth muscle cells (hDASMC).
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Anomalous Right Coronary Artery Arising From Distal Left Circumflex Artery.
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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
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Using health administrative data to identify patients with pulmonary hypertension: A single center, proof of concept validation study in Ontario, Canada.
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Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
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Exertional Dyspnea and Chronotropic Incompetence Caused by Extrinsic Compression of the Right Carotid Body by a Giant Lipoma.
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SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia.
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An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats.
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A Multi-omic and Multi-Species Analysis of Right Ventricular Failure.
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Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension.
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Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension.
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Concept
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Imatinib Mesylate
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Concept
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Sildenafil Citrate
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Concept
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Ranolazine
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Concept
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Venlafaxine Hydrochloride
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Concept
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Health Equity
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Concept
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NLR Family, Pyrin Domain-Containing 3 Protein
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Concept
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Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
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Concept
|
Soluble Guanylyl Cyclase
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Concept
|
NADPH Oxidase 2
|
Concept
|
DNA (Cytosine-5-)-Methyltransferase 1
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Concept
|
RNA, Long Noncoding
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Concept
|
Hernias, Diaphragmatic, Congenital
|
Concept
|
Calcineurin Inhibitors
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Concept
|
Endothelin Receptor Antagonists
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Concept
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Familial Primary Pulmonary Hypertension
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Concept
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Vascular Remodeling
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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Academic Article
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Asymptomatic surveillance testing for COVID-19 in health care professional students: lessons learned from a low prevalence setting.
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Using omics to breathe new life into our understanding of the ductus arteriosus oxygen response.
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Academic Article
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Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus.
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Academic Article
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The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases.
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Multi-omic and multispecies analysis of right ventricular dysfunction.
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Academic Article
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The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases.
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Complete Revascularization of the Pulmonary Circulation in Chronic Thromboembolic Pulmonary Hypertension: Value of Addressing Chronic Total Occlusions.
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Academic Article
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The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
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Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury.
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Academic Article
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Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension.
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Academic Article
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Pulmonary hypertension.
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Academic Article
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Germline and Somatic Mutations in DNA Methyltransferase 3A (DNMT3A) Predispose to Pulmonary Arterial Hypertension (PAH) in Humans and Mice: Implications for Associated PAH.
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